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How long before Spironolactone works for acne?

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Rated Spironolactone (Aldactone) for Acne Slowly increased from 25 to 100 mg. Improvement began 4 months in with 100 mg per day AND a time release minocycline for 2 months. Been off the minocycline for about a month now. Side effects are breast pain when period approaching and slightly shorter period cycle.
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